connexin43相关论文
目的:探讨缝隙连接蛋白Connexin43（Cx43）在脑出血（intracerebral hemorrhage,ICH）后继发性损伤中的作用机制及外胚间充质干细胞（ecto-me......
抑郁症是最常见的心境障碍疾病。在人的一生中,抑郁症的发病率是12%-17%。据世界卫生组织的报道,在全世界范围内有3.4亿的抑郁症患......
学位
目的:探讨Cx43在肺动脉高压（pulmanory arterial hypertension,PAH）中的作用及其相关机制。方法:1、通过慢性低氧和腹腔注射野百合碱......
第一部分:TRPV4参与大鼠无菌性心包炎模型心房颤动的发生目的:建立稳定的大鼠无菌性心包炎心房颤动（房颤）模型,观察TRPV4在无菌性心......
目的:评价低温缺氧复氧时大鼠心肌成纤维细胞(RCF)对H9c2细胞缝隙连接蛋白43(Cx43)表达的影响。方法:体外培养的H9c2细胞，采用随机......
Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial C
Rictor is a key component of the mammalian target of rapamycin complex 2 (mTORC2) and is required for Akt phosphorylatio......
Osteocytes are the main sensitive cells in bone remodeling due to their potent functional cell pro-cesses from the miner......
The mechanisms through which auricular vagus nerve stimulation protects against cerebral ischemia/re
Previous studies have shown that vagus nerve stimulation can improve patients\' locomotor function. The stimulation of......
Impaired osteogenic differentiation associated with connexin43/microRNA-206 in steroid-induced avasc
Objective Connexin(Cx)43 and microRNA(miR)-206 play an important role in osteogenesis. However, their role in steroid in......
Heterotopic ossification(HO)can result from traumatic injury,surgery or genetic diseases.Here,we demonstrate that overex......
Objective This study is to observe the mechanism of the astrocytes regulating activation of the neurons induced by hypot......
Beyond gap junction channel function: the expression of Cx43 contributes to aldosterone-induced mesa
Aims: This study aimed to explore the precise mechanism and signaling pathways of mesangial cell (MC) proliferation from......
Intercellular communication through gap junctions plays an essential role in maintaining the functional integrity of vas......
Growing evidence has implicated glial anomalies in the pathophysiology of major depression disorder (MDD).Gap junctional......
Background/Aims: Connexin43 (Cx43) belongs to a family of transmembrane protein that build cell-to-cell channels in gap ......
Role of gap junction intercellular communication in H9c2 cardiomyocytes cell apoptosis induced by si
Gap junction intercellular communication(GJIC)between cardiomyocytes is essential for synchronous heart contraction and ......
Expression and significance of mitogen-activated protein kinase pathway and connexin43 in myometrium
Objective To explore the significance of activated mitogen-activated protein kinase (MAPK)pathway and Connexin 43 expres......
Background context Spinal cord injury (SCI) is a serious health issue that may result in high health care costs, with ad......
Wide QRS complex in electrocardiogram is one of the risk factors for morbidity and mortality in many kinds of cardiac di......
Tumor-suppressor microRNA-139-5p restrains bladder cancer cell line ECV-304 properties via targeting
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研究细胞间隙连接蛋白基因 43(connexin43,CX43)及其蛋白、雌激素受体 (estrogen receptor,ER)、孕激素受体 (progesterone recept......
间隙连接(GJ)是细胞膜上的连接通道结构,由整合膜蛋白-间隙连接蛋白(Cx)亚单位构成,它所介导的细胞间隙连接通讯(GJIC)在细胞间传......
目的探讨氧糖剥夺(oxygen-glucose deprivation，OGD)条件下脑星形胶质细胞缝隙连接与糖摄取功能之间关系。方法取出生1 d的SD大鼠大......
Perinatal encephalopathy remains a major cause of disability, such as cerebral palsy. Therapeutic hypo-thermia is now we......
细胞间隙连接通讯(gap junction intercellular communication,GJIC)对于细胞增殖、分化、内环境稳定及机体新陈代谢、生长发育等......
期刊
目的 探讨胚胎期雄激素受体阻滞剂氟他胺(flutamide,Flu)暴露对睾丸间隙连接蛋白43 (Connexin43,Cox43)基因表达的影响.方法 在胚......
目的利用转缝隙连接蛋白43/闭锁小带-1(CX43/ZO-1)双基因诱导多能干细胞(iPS细胞)移植猪心肌梗死模型观察对梗死心肌的治疗效果。......
目的 观察心室纤颤(室颤)发生后缝隙连接蛋白Cx43的表达以及缝隙连接改造剂ZP123对Cx43表达的影响.方法 按照随机数字表法将30只家......
目的探讨山莨菪碱对心搏骤停猪复苏后心室肌缝隙连接蛋白43（Cx43）表达的影响。方法选择健康家猪进行实验，按随机数字表法分为假手术组......
目的 研究乌灵胶囊改善阿尔茨海默病模型小鼠(5×FAD)认知功能及缝隙连接蛋白43(Cx43)的作用机制.方法 用随机区组法将5×FAD小鼠......
目的构建间隙连接蛋白43（CX43）过表达载体，并对其进行鉴定。方法用内切酶EcoRI、XbaI双酶切含目的基因的质粒和慢病毒载体，将目的基因......
目的 探讨桉叶油联合维甲酸(RA)对SD胎鼠脑组织转录因子Pax3、缝隙连接蛋白43(Cx43)表达的影响.方法SD孕鼠42只,随机分为6组,每组7......
CMYA1(cardiomyopathy-associated protein 1,also termed Xin)localizes to the intercalated disks(ICDs)of the myocardium and......
目的:足细胞损伤是糖尿病肾病(DN)进展的重要环节,早期以蛋白尿为主要临床表现。并且,自噬功能受损与足细胞消失的发病机制有关。......
研究背景口腔鳞状细胞癌(oral squamous cell carcinoma,OSCC)是口腔颌面部常见的恶性肿瘤,过去十年其发病率增加了50%,大多发生在......
目的 观察单纯疱疹病毒胸苷激酶(HSV-TK)/丙氧鸟苷(GCV)系统联合全反式维甲酸(ATRA)对人雄激素非依赖性前列腺癌PC-3细胞旁观者效......
Objective: The aim of our study was to investigate the effects of (-)-epigallocatechin-3-gallate (EGCG, the major phytoc......
Improvement of cardiac function and reversal of gap junction remodeling by Neuregulin-1β in volume-o
Objective We performed experiments using Neuregulin-1β (NRG-1β) treatment to determine a mechanism for the protective ......
目的探讨人类瓣膜病慢性心房颤动(房颤)心房肌中缝隙连接通道蛋白Connexin 43(CX43)和Connexin 40(CX40)的重构及其与房颤的关系.......
为了探讨细胞间隙连接ｃｏｎｎｅｘｉｎ（ｃｘ）基因及其蛋白产物在肝癌细胞系的表达及意义，应用核酸分子原位杂交和流式细胞仪分析技术，研究肝癌细胞系ＨＨＣＣ、ＳＭＭＣ７７２１和......
Objective: To study the expression of connexin43 (Cx43) gene and its correlation with the apoptosis related genes Bcl-2 ......
目的:探讨补阳还五汤对大鼠脑缺血再灌注后海马CA1区缝隙连接小体connexin43(Cx43)的影响。方法:采用颈内动脉线栓法建立大脑中动......
目的:探讨补阳还五汤对大鼠脑缺血再灌注后星形胶质细胞缝隙连接蛋白43(connexin43,Cx43)的影响机制。方法:运用线栓法建立大脑中......
目的:研究肿瘤坏死因子-α(TNF-α)对大鼠心肌梗死后连接蛋白(Cx)43重构调节作用及其对室性心律失常发生的影响。方法:采用液氮冷......
本文从缝隙连接通讯(GJIC)及connexin43(Cx43)在骨质疏松及相关疾病的研究进展进行综述，研究结果表明Cx43与骨质疏松性疾病的发生和......
